The Washington Commanders' recent ineptitude on first-round draft picks was on display again Saturday, as the team waived ...

Running back Christian McCaffrey says the 49ers are “hungry” to make a playoff push even with the defending NFC champions ...

The #Bills have activated Pro Bowl LB Matt Milano off Injured Reserve and he’ll play on Sunday against the #49ers for the ...

Analyzing Sunday’s San Francisco 49ers at Buffalo Bills odds and lines, with expert NFL picks and predictions.

Highest snow accumulations expected east of Lake Ontario, where some isolated areas could get hit by up to 60 inches of snow.

Buffalo Bills offensive stars prepare to shine against the San Francisco 49ers' struggling defense in a critical AFC-NFC ...

Charlotte football ended its season victorious. With the 49ers holding a 29-27 lead during the final minutes, Alabama ...

The Buffalo Bills will look to clinch the AFC East on Sunday with a win against the San Francisco 49ers in what's expected to ...

Dre Greenlaw practiced for the first time this week since he tore his Achilles in the Super Bowl. Here's what head coach Kyle ...

The lake-effect storm disrupted holiday plans and travel across the region. National Guard troops were dispatched in New York ...

According to Cam Inman, the 49ers are signing CB Nick McCloud to the 53-man roster. McCloud takes the place of WR Ronnie Bell ...

Former Chicago Bears head coach Matt Eberflus issued a gracious statement to the players and fans after being fired Friday in ...