The San Francisco 49ers aren't in the position they want to be right now and it seems like this just isn't their year.

NFL Week 14 waiver wire cheat sheet for all league sizes and formats, with players you need to add, drop and stream in your ...

Isaac Guerendo and Will Levis are among UPI senior sports writer Alex Butler's top fantasy football waiver wire priorities ...

Rookie Isaac Guerendo steps up as 49ers seek to fill void left by McCaffrey and injured backup Jordan Mason. Coach Shanahan ...

The San Francisco 49ers' playoff chances took a significant hit Sunday following a 35-10 loss to the Buffalo Bills at ...

The first games of the holiday season are in the books as the road to the NFL playoffs continues. Week 13 saw a stereotypical ...

The San Francisco 49ers injury list continues to grow in the second half of the season. Following their Week 13 loss to the ...

Christian McCaffrey may have suffered an isolated PCL tear against the Buffalo Bills, a rare injury that could end his season ...

After missing the first eight games with an Achilles injury to begin the season, running back Christian McCaffrey will be ...

Former Mexican boxer Israel Vazquez, who won three junior featherweight world titles, died after battling cancer, World ...

On a night when Josh Allen threw a touchdown pass and scored one on the same play, the strangest sight at snowy Highmark ...

Back-to-back blowout losses and another injury to star back Christian McCaffrey might just be the final blow to the dwindling ...